发信人: Jacob (Jack), 信区: JobMarket
标 题: Postdoc fellow to study addiction using operant conditioning (or electrophysiology) and optogenetics
关键字: optogenetics,operant conditioning,patch-clamp,addiction
发信站: BBS 未名空间站 (Wed Oct 9 20:20:55 2019, 美东)
•An NIH-funded postdoctoral position is immediately available to
investigate synaptic and circuit mechanisms of drug and alcohol addiction.
Research in the lab utilizes state-of-the-science technologies, including in
vivo dual-channel optogenetic (see our recent paper , https://www.nature.
com/articles/s41593-018-0081-9) and chemogenetic (DREADDs, see https://www.
manipulation of striatal neuron activities, fiber photometry, rabies-
mediated brain-wide neuronal mapping, and FosTRAP approaches in combination
with behavioral procedures (e.g., operant alcohol self-administration) and
slices electrophysiology. We investigate how medium spiny neurons and
cholinergic interneurons in the dorsomedial striatum of the basal ganglia
circuitry contribute to alcohol, cocaine, and morphine abuse. For details,
please visit: https://medicine.tamhsc.edu/faculty/wang.html and http://people.tamu.edu/~jwang188/.
•We are seeking a highly-motivated behavioral scientist. The
successful candidates are expect to have trackable records on operant self-
administration, in vivo optogenetic stimulation, or fiber photometry
measurement. Ability to stereotaxically infuse viruses in rats or mice is
required. Experience with optogenetics, chemogenetics, immunohistochemistry,
or confocal imaging is a big plus. The successful applicants are expected
to have a recent PhD degree in neuroscience, strong communication skills and
writing ability, a record of scientific productivity, and a desire to work
independently and cooperatively with a team. The candidate will have
opportunities to learn slice electrophysiology.
•Applicants with solid electrophysiology backgrounds and strong
interests in using behavioral approaches are also welcome to apply. The
successful candidates are expect to have proven proficiency in slice
electrophysiology and will study circuit-specific alterations. Ability to
measure glutamatergic plasticity in acute slices using whole-cell patch-
clamp recording is desired. Experience with optogenetics, chemogenetics,
immunohistochemistry, or confocal imaging is a big plus.
•Interested candidates should send Curriculum Vitae and names of three
references to Dr. Jun Wang ([email protected]).
•About the institution: Texas A&M University (TAMU) is a research-
intensive flagship university of the Texas A&M system. TAMU is the largest
university in Texas and the third largest in the US, with an annual
enrollment that exceeds 69,000 students. In 2017, 14,998 graduate students
were enrolled among 268 different graduate degree programs. Among the 19
TAMU component colleges, the colleges of liberal arts, sciences, agriculture
and life sciences, engineering and veterinary medicine, as well as the
Texas A&M Health Science Center (TAMHSC, Medicine, Nursing, Public Health
and Pharmacy) are located on a 5,200-acre campus in the twin cities of Bryan
and College Station, with a short drive to three major Texas cites --
Houston (1.5 hours), Austin (2 hours) and Dallas (< 3 hours). This vicinity
provides not only an easy access to big-city life, but also less traffic,
cheaper housing, county life such as fishing. The George Bush Presidential
Library and Museum is one of the region's most popular tourist attractions
with approximately 700,000 visitors annually. Within this campus, there is a
large group of neuroscience laboratories, some of which study drug abuse.
The department of Neuroscience and Experimental Therapeutics is located in a
new building of the Bryan campus, which provides a really nice working
environment. The postdoc position is a full-time position with benefits. The
benefits available to all staff members are outlined here: http://www.tamus.edu/assets/files/benefits/pdf/GuideBooklet.pdf.
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